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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878572Generated: November 3, 2026

3-Chloro-4-fluorobenzyl alcohol → 2-{5-[(3-chloro-4-fluorobenzyl)oxy]-1H-pyrazol-1-yl}pyridine-4-carbonitrile

https://huagongshe.com/reaction/878572

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorobenzyl alcoholHCID 2773607—
ReactantHCID 178510213HCID 178510213—
Product2-{5-[(3-chloro-4-fluorobenzyl)oxy]-1H-pyrazol-1-yl}pyridine-4-carbonitrileHCID 86725540—

Reaction Steps

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (3-chloro-4-fluorophenyl)methanol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C16H10ClFN4O, 329; Found, 329.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-7741a15bfc9e4ec480df6380ad2aa9ce
Source noteuspto-grants-2015_03