4-Fluorobenzylic alcohol → HCID 86725549, compound

HRID 878582Notes

Reaction equation

HRID 878582 reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][N:6]([C:9]2[CH:14]=[C:13]([C:15]#[N:16])[CH:12]=[CH:11][N:10]=2)[C:7]=1[OH:8])[CH3:2].[F:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22]O)=[CH:20][CH:19]=1>>[CH2:1]([C:3]1[CH:4]=[N:5][N:6]([C:9]2[CH:14]=[C:13]([C:15]#[N:16])[CH:12]=[CH:11][N:10]=2)[C:7]=1[O:8][CH2:22][C:21]1[CH:24]=[CH:25][C:18]([F:17])=[CH:19][CH:20]=1)[CH3:2]

Participants

3

Reactant 2

HCID 680224-Fluorobenzylic alcoholHCID 178437219HCID 178437219, compound

Product 1

HCID 86725549HCID 86725549, compound

Procedure

The title compound was prepared from 2-(4-ethyl-5-hydroxypyrazol-1-yl)pyridine-4-carbonitrile and 4-fluorobenzyl alcohol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C18H15FN4O, 323; Found, 323.

Sources & evidence

ORD record
ord-a3ffcf1b9de94a2eaf0beab407ee59a8
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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