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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878601Generated: October 30, 2026

3-(Hydroxymethyl)benzonitrile → Methyl 2-[5-[(3-cyanophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylate

https://huagongshe.com/reaction/878601

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Hydroxymethyl)benzonitrileHCID 2734677—
ReactantHCID 178498428HCID 178498428—
ProductMethyl 2-[5-[(3-cyanophenyl)methoxy]pyrazol-1-yl]pyridine-4-carboxylateHCID 86725565—

Reaction Steps

The title compound was prepared from methyl 2-(5-hydroxypyrazol-1-yl)pyridine-4-carboxylate (PREPARATION 6) and (3-cyanophenyl)methanol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C18H14N4O3, 335; Found, 335.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-173607fdd6294f9ca879832ebfa3840c
Source noteuspto-grants-2015_03