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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878614Generated: October 26, 2026

[4-Chloro-2-(cyclopropylmethoxy)phenyl]methanol → 2-[5-[[4-Chloro-2-(cyclopropylmethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carbonitrile

https://huagongshe.com/reaction/878614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[4-Chloro-2-(cyclopropylmethoxy)phenyl]methanolHCID 86725580—
ReactantHCID 178510213HCID 178510213—
Product2-[5-[[4-Chloro-2-(cyclopropylmethoxy)phenyl]methoxy]pyrazol-1-yl]pyridine-4-carbonitrileHCID 86725581—

Reaction Steps

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and [4-chloro-2-(cyclopropylmethoxy)phenyl]methanol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C20H17ClN4O2, 381; Found, 381.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-230aa1d7852644698655d6f59075f031
Source noteuspto-grants-2015_03