Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878648Generated: October 31, 2026

4-Fluorostyrene → [4-chloro-2-[(E)-2-(4-fluorophenyl)ethenyl]phenyl]methanol

https://huagongshe.com/reaction/878648

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorostyreneHCID 67883—
Reactant(2-Bromo-4-chlorophenyl)methanolHCID 54049764—
Product[4-chloro-2-[(E)-2-(4-fluorophenyl)ethenyl]phenyl]methanolHCID 86725610—

Reaction Steps

The title compound was prepared from (2-bromo-4-chlorophenyl)methanol and 4-fluoro-1-vinylbenzene according to the procedure for the preparation of Example 119, part B. 1H NMR (400 MHz, CDCl3): δ 1.72 (1H, t, J=5.6 Hz), 4.77 (2H, d, J=5.2 Hz), 6.98-7.08 (3H, m), 7.22-7.34 (3H, m), 7.47-7.50 (2H, m), 7.60 (1H, d, J=1.6 Hz).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-12be53f4989741eea0ed8e2e397d2429
Source noteuspto-grants-2015_03