6-Chloro-1,2,3,4-tetrahydro-1-naphthalenol → HCID 86725649, compound

HRID 878696Notes

Reaction equation

HRID 878696 reaction equation
[OH:1][C:2]1[N:6]([C:7]2[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=2)[N:5]=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH:22](O)[CH2:21][CH2:20][CH2:19]2>>[Cl:15][C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH:22]([O:1][C:2]1[N:6]([C:7]3[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=3)[N:5]=[CH:4][CH:3]=1)[CH2:21][CH2:20][CH2:19]2

Participants

3

Reactant 2

HCID 126949186-Chloro-1,2,3,4-tetrahydro-1-naphthalenolHCID 178510213HCID 178510213, compound

Product 1

HCID 86725649HCID 86725649, compound

Procedure

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and 6-chloro-1,2,3,4-tetrahydronaphthalen-1-ol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C19H15ClN4O, 351; Found, 351.

Sources & evidence

ORD record
ord-aad1dbb10d8c4a798665c696696b6e33
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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