HCID 86725653, compound → HCID 86725652, compound

HRID 878704Notes

Reaction equation

HRID 878704 reaction equation
[OH:1][C:2]1[N:6]([C:7]2[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=2)[N:5]=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[C:20]([CH:22]2[CH2:24][CH2:23]2)[CH:19]=[CH:18][C:17]=1[CH2:25]O>>[Cl:15][C:16]1[CH:21]=[C:20]([CH:22]2[CH2:24][CH2:23]2)[CH:19]=[CH:18][C:17]=1[CH2:25][O:1][C:2]1[N:6]([C:7]2[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=2)[N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 86725653HCID 86725653, compoundHCID 178510213HCID 178510213, compound

Product 1

HCID 86725652HCID 86725652, compound

Procedure

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (2-chloro-4-cyclopropylphenyl)methanol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C19H15ClN4O, 351; Found, 351.

Sources & evidence

ORD record
ord-42f82f37883648ef8a31d8e5c1e47c8d
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

Loading…