Ethyl 3-oxo-4-phenylpentanoate → HCID 178435908, compound

HRID 878724Notes

Reaction equation

HRID 878724 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].O=[C:12]([CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH3:20])[CH2:13][C:14](OCC)=[O:15]>>[OH:15][C:14]1[N:1]([C:3]2[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=2)[N:2]=[C:12]([CH:19]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH3:20])[CH:13]=1

Participants

3

Reactant 2

HCID 11127801Ethyl 3-oxo-4-phenylpentanoateHCID 201187142-Hydrazinylpyridine-4-carbonitrile

Product 1

HCID 178435908HCID 178435908, compoundYield 40%

Procedure

The title compound was prepared in 40% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 3-oxo-4-phenylpentanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-0f3be0b026c049519d98dacd1b96bdd5
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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