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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878729Generated: October 26, 2026

(4-Chlorophenyl)acetic acid → Ethyl 4-(4-chlorophenyl)-3-oxobutanoate

https://huagongshe.com/reaction/878729

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chlorophenyl)acetic acidHCID 15880—
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
ProductEthyl 4-(4-chlorophenyl)-3-oxobutanoateHCID 1084766343%

Reaction Steps

The title compound was prepared in 43% yield from 2-(4-chlorophenyl)acetic acid and 2,2-dimethyl-1,3-dioxane-4,6-dione according to the procedure for the preparation of Example 162, part A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987461B2
Source datasetuspto-grants-2015_03
ORD IDord-4b6c1de43fac4212b99a2d7870dbd28a
Source noteuspto-grants-2015_03