2-Hydrazinylpyridine-4-carbonitrile → HCID 178439127, compound

HRID 878733Notes

Reaction equation

HRID 878733 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]([CH3:27])([CH3:26])[C:19](=O)[CH2:20][C:21](OC)=[O:22])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:13]=[CH:14][C:15]([C:18]([C:19]2[CH:20]=[C:21]([OH:22])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)([CH3:27])[CH3:26])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 201187142-Hydrazinylpyridine-4-carbonitrileHCID 86725679HCID 86725679, compound

Product 1

HCID 178439127HCID 178439127, compound

Procedure

The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 4-(4-chlorophenyl)-4-methyl-3-oxopentanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-5079804b131744ea9121746a2ea8144e
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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