2-Hydrazinylpyridine-4-carbonitrile → HCID 178510207, compound

HRID 878735Notes

Reaction equation

HRID 878735 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2([C:21](=O)[CH2:22][C:23](OC)=[O:24])[CH2:20][CH2:19]2)=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:13]=[CH:14][C:15]([C:18]2([C:21]3[CH:22]=[C:23]([OH:24])[N:1]([C:3]4[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=4)[N:2]=3)[CH2:19][CH2:20]2)=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 201187142-Hydrazinylpyridine-4-carbonitrileHCID 86725681HCID 86725681, compound

Product 1

HCID 178510207HCID 178510207, compound

Procedure

The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 3-[1-(4-chlorophenyl)cyclopropyl]-3-oxopropanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-2f12a94e076745f39be2d81d64e24489
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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