2-Hydrazinylpyridine-4-carbonitrile → HCID 178510219, compound
Reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][C:20](=O)[CH2:21][C:22](OC)=[O:23])[CH:15]=[C:16]([Cl:18])[CH:17]=1>>[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][C:20]2[CH:21]=[C:22]([OH:23])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)[CH:15]=[C:16]([Cl:18])[CH:17]=1Participants
3
Procedure
The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 4-(3,5-dichlorophenyl)-3-oxobutanoate according to the procedure for the preparation of Example 158, part A.
Sources & evidence
- ORD record
- ord-ecb1063ca1504445a73e9f9dbab17d3e
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08987461B2
Reaction notes
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