2-Hydrazinylpyridine-4-carbonitrile → HCID 178510218, compound

HRID 878742Notes

Reaction equation

HRID 878742 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[F:11][C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1[CH2:19][C:20](=O)[CH2:21][C:22](OC)=[O:23]>>[F:11][C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1[CH2:19][C:20]1[CH:21]=[C:22]([OH:23])[N:1]([C:3]2[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=2)[N:2]=1

Participants

3

Reactant 2

HCID 201187142-Hydrazinylpyridine-4-carbonitrileHCID 26597804HCID 26597804, compound

Product 1

HCID 178510218HCID 178510218, compound

Procedure

The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 4-(2,4-difluorophenyl)-3-oxobutanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-0921f7443ec04e63a9a56450909e02b2
Source dataset
uspto-grants-2015_03
Patent number
US08987461B2

Reaction notes

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