HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-(chloromethyl)-3-fluorobenzene → 2-(1-benzyl-1H-indole-6-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-(chloromethyl)-3-fluorobenzene | HCID 108675 | — |
| Reactant | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| Product | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| Product | 2-[1-(2-chloro-6-fluorobenzyl)-1H-indole-6-yl]acetic acid | HCID 68184348 | — |
Reaction Steps
The titled compound (40 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-chloro-6-fluorobenzyl chloride according to the method of the process (7) of Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987473B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-b64c8a4ef2864747acfaff42813c3cd7 |
| Source note | uspto-grants-2015_03 |