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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878960Generated: October 29, 2026

p-Trifluoromethylbenzyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/878960

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Trifluoromethylbenzyl chlorideHCID 123096—
Reactant2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
ProductHCID 68184487HCID 68184487—

Reaction Steps

The titled compound (33 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 4-(trifluoromethyl)benzyl chloride according to the method of the process (7) of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987473B2
Source datasetuspto-grants-2015_03
ORD IDord-858dcf5e9a4e414890a64be59549bf67
Source noteuspto-grants-2015_03