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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 878985Generated: October 26, 2026

tert-Butyl 6-bromoindoline-1-carboxylate → tert-butyl 6-allyl-2,3-dihydro-1H-indole-1-carboxylate

https://huagongshe.com/reaction/878985

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 6-bromoindoline-1-carboxylateHCID 22038386—
Reactant1-(2,6-dimethylbenzyl)-3-methyl-1H-indole-6-carboxylic acidHCID 60152006—
Producttert-butyl 6-allyl-2,3-dihydro-1H-indole-1-carboxylateHCID 68184274—

Reaction Steps

The titled compound (5.7 g) as a colorless oil was prepared from tert-butyl 6-bromo-2,3-dihydro-1H-indole-1-carboxylate (7.5 g) obtained with the method described in the document (WO 1998/43956 A) according to the method of the process (2) of Example 66.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987473B2
Source datasetuspto-grants-2015_03
ORD IDord-df20a26d11434ad98ec80b1cce311806
Source noteuspto-grants-2015_03