1H-Pyrrolo(2,3-b)pyridine → HCID 178526243, compound

Participants

Reaction Steps

To a solution of 1H-pyrrolo[2,3-b]pyridine (495 mg) in 1,2-dimethoxyethane (20 mL) was added 3-chloroperbenzoic acid (1.48 g) at room temperature, and then the reaction mixture was stirred at room temperature for 2 hours. The reaction mixture was quenched with water, and extracted with chloroform. The obtained organic layer was dried over anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure. The obtained residue was purified by silica gel column chromatography to give the titled compound (360 mg) as a white solid.

Provenance & Evidence