Potassium Hydroxide → HCID 131732624, compound

HRID 879002Notes

Reaction equation

HRID 879002 reaction equation
[CH3:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:14]([OH:16])=[O:15])[CH:12]=2)[C:7]([CH3:17])=[N:6]1.[OH-].[K+:24]>C(O)C>[CH3:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:14]([O-:16])=[O:15])[CH:12]=2)[C:7]([CH3:17])=[N:6]1.[K+:24]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 68184383HCID 68184383, compound

Product 1

HCID 131732624HCID 131732624, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of the compound [117](568 mg) in ethanol (20 mL) was added an aqueous solution of 1N-potassium hydroxide (1.93 mL) at room temperature, and then the reaction mixture was stirred at room temperature for 10 minutes. The reaction mixture was concentrated under reduced pressure to give the titled compound (636 mg) as a white solid.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-d932c1bea52f4eb29596f6a8439aed56
Source dataset
uspto-grants-2015_03
Patent number
US08987473B2

Reaction notes

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