Potassium Hydroxide → HCID 131732625, compound

HRID 879007Notes

Reaction equation

HRID 879007 reaction equation
[Cl:1][C:2]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([CH2:14][C:15]([OH:17])=[O:16])[CH:12]=2)[C:7]([CH2:18][CH3:19])=[N:6]1.[OH-].[K+:26]>C(O)C>[Cl:1][C:2]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([CH2:14][C:15]([O-:17])=[O:16])[CH:12]=2)[C:7]([CH2:18][CH3:19])=[N:6]1.[K+:26]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 60152154HCID 60152154, compound

Product 1

HCID 131732625HCID 131732625, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of the compound [140](42 mg) in ethanol (1 mL) was added an aqueous solution of 1N-potassium hydroxide (116 μL) at room temperature, and the solution was concentrated under reduced pressure to give the titled compound (110 mg) as a white solid.

Workup

  1. concentrationthe solution was concentrated under reduced pressure

Sources & evidence

ORD record
ord-35b2b58274344cc89fb014a542515a88
Source dataset
uspto-grants-2015_03
Patent number
US08987473B2

Reaction notes

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