HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 6-bromo-5-fluoropyridine-2-carboxylate → HCID 70655145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 6-bromo-5-fluoropyridine-2-carboxylate | HCID 46311204 | — |
| Reactant | HCID 70655078 | HCID 70655078 | — |
| Product | HCID 70655145 | HCID 70655145 | — |
Reaction Steps
Method 1 was followed using methyl 6-bromo-5-fluoropicolinate (0.8 equiv.) and 2-(2,6-difluoro-4-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1.0 equiv.) at 70° C. for 1 hour to give methyl 6-(2,6-difluoro-4-isopropoxyphenyl)-5-fluoropicolinate. LC/MS=325.9 (MH+), Rt=1.04 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987457B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-01b6c1a5f4204613820a7edc8bca3d5b |
| Source note | uspto-grants-2015_03 |