Iodoethane → HCID 86699803, compound

Participants

Reaction Steps

To a solution of (S)-2-(2-(3-bromophenyl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetic acid (104 mg, 0.191 mmol) in DMF, was added Cs2CO3 (152 mg, 0.467 mmol), ethyl iodide (30 μL, 0.343 mmol). The reaction was stirred at room temperature for 2hs. The reaction mixture was washed by sat. NaHCO3, extracted by EtOAc, dry over MgSO4, filtered, purified by silica gel column, eluting by 0-50% EtOAc in hexanes to give the product. LCMS-ESI+: calc'd for C28H27BrClNO3S: 572.1 (M+H+); Found: 572.2 (M+H+).

Provenance & Evidence