5-Bromo-1-methyl-2-oxoindoline → HCID 86700270, compound

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(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(2-(1-methyl-2-oxoindolin-5-yl)pyridin-4-yl)benzo[d]thiazol-6-yl)acetic acid was prepared using in a similar manner as (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(2-(1-methyl-2-oxoindolin-4-yl)pyridin-4-yl)benzo[d]thiazol-6-yl)acetic acid, except 5-bromo-1-methylindolin-2-one was used instead of 4-bromo-1-methylindolin-2-one. LCMS-ESI+: calc'd for C34H31ClN3O4S: 612.1 (M+H+); Found: 612.2 (M+H+). 1H NMR (400 MHz, CD3OD) δ: 8.61 (d, 1H), 8.36 (s, 1H), 7.94 (d, 1H), 7.89 (m, 1H), 7.84 (m, 2H), 7.61-7.59 (m, 1H), 7.54-7.50 (m, 3H), 7.03 (d, 1H), 5.18 (s, 1H), 3.55 (s, 2H), 3.14 (s, 3H), 2.53 (s, 3H), 0.89 (s, 9H).

Provenance & Evidence