5-Bromo-2-oxindole → (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(2-oxoindolin-5-yl)benzo[d]thiazol-6-yl)acetic acid

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(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(2-oxoindolin-5-yl)benzo[d]thiazol-6-yl)acetic acid was prepared in a similar manner as (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-2-oxoindolin-5-yl)benzo[d]thiazol-6-yl)acetic acid except 5-bromoindolin-2-one was used instead of 5-bromo-1-methylindolin-2-one. LCMS-ESI+: calc'd C28H26ClN2O4S: 521.1 (M+H+); Found: 521.2 (M+H+). 1H NMR (400 MHz, CD3OD) δ: 7.91-7.88 (m, 2 H), 7.77 (s, 1H), 7.66 (m, 1H), 7.59-7.56 (m, 2H), 6.99 (d, 1H), 5.23 (s, 1H), 3.61 (s, 2H), 2.63 (s, 3H), 2.59 (s, 3H), 0.96 (s, 9H).

Provenance & Evidence