3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride → HCID 72196115, compound

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Prepared in a similar manner as (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(7,8-dihydro-1,6-naphthyridin-6(5H)-yl)-5-methylbenzo[d]thiazol-6-yl)acetic acid except using 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride instead of 5,6,7,8-tetrahydro-1,6-naphthyridine, dihydrochloride, hydrate. LCMS-ESI+: calc'd for C26H25ClF3N5O3S: 580.1, 582.1 (M+H+); Found: 580.2, 582.2 (M+H+). 1H NMR (400 MHz, CD3OD): δ 7.72-7.45 (m, 4H), 7.41 (s, 1H), 5.16 (s, 1H), 5.09 (s, 2H), 4.38 (t, J=5.4 Hz, 2H), 4.11 (t, J=5.5 Hz, 2H), 2.51 (s, 3H), 0.95 (s, 2H).

Provenance & Evidence