HCID 86700290, compound → HCID 86700289, compound

HRID 879476Notes

Reaction equation

HRID 879476 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].CN1C2CCNCC=2C(C)=N1.[CH3:19][N:20]1[C:35]([CH3:36])=[C:23]2[CH2:24][N:25](C(OC(C)(C)C)=O)[CH2:26][CH2:27][C:22]2=[N:21]1>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH3:19][N:20]1[C:35]([CH3:36])=[C:23]2[CH2:24][NH:25][CH2:26][CH2:27][C:22]2=[N:21]1

Participants

3

Reactant 2

HCID 86700290HCID 86700290, compoundHCID 86700291HCID 86700291, compound

Product 1

HCID 86700289HCID 86700289, compound

Procedure

Prepared in a manner similar to 1,3-dimethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine trifluoroacetic acid salt, except using tert-butyl 2,3-dimethyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate instead of tert-butyl 1,3-dimethyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate. LCMS-ESI+: calc'd for C8H13N3: 152.1 (M+H+); Found: 152.0 (M+H+).

Sources & evidence

ORD record
ord-86038c299e5f4bdc97d83c6c5912862f
Source dataset
uspto-grants-2015_03
Patent number
US08987250B2

Reaction notes

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