5-Bromo-1-methyl-1H-indazol-3-amine → (S)-ethyl 2-(2-(3-amino-1-methyl-1H-indazol-5-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetate

Participants

Role	Name	HCID	Charge
Reactant	5-Bromo-1-methyl-1H-indazol-3-amine	HCID 26369215	—
Reactant	(S)-ethyl 2-(2-(3-amino-1-methyl-1H-indazol-6-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetate	HCID 86700305	—
Product	(S)-ethyl 2-(2-(3-amino-1-methyl-1H-indazol-5-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetate	HCID 86700310	—

Reaction Steps

Prepared in a manner similar to (S)-ethyl 2-(2-(3-amino-1-methyl-1H-indazol-6-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetate except using 5-bromo-1-methyl-1H-indazol-3-amine instead of 6-bromo-1-methyl-1H-indazol-3-amine. LCMS-ESI+: calc'd for C30H31ClN4O3S: 563.2, 565.2 (M+H+); Found: 563.3, 565.2 (M+H+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08987250B2
Source dataset	uspto-grants-2015_03
ORD ID	ord-7441b71de8ef4c81acaa9627aef6e49b
Source note	uspto-grants-2015_03