HCID 86700321, compound → HCID 86700322, compound

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(2S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(3-(1-methyl-1H-indazol-5-yl)-2-oxopiperazin-1-yl)benzo[d]thiazol-6-yl)acetic acid (5 mg) was prepared in a similar manner as compound (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(3-(1-methyl-1H-indazol-5-yl)-2-oxopyrazin-1 (2H)-yl)benzo[d]thiazol-6-yl)acetic acid except using (2S)-ethyl 2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(3-(1-methyl-1H-indazol-5-yl)-2-oxopiperazin-1-yl)benzo[d]thiazol-6-yl)acetate instead of (S)-ethyl 2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(3-(1-methyl-1H-indazol-5-yl)-2-oxopyrazin-1(2H)-yl)benzo[d]thiazol-6-yl)acetate. LCMS-ESI+: calc'd for C32H33ClN5O4S: 618.2 (M+H+); Found: 618.1 (M+H+). 1H-NMR 400 MHz, (CDCl3) δ 7.99 (m, 1H), 7.74-7.60 (m, 3H), 7.43-7.35 (m, 4H), 7.3-7.2 (m, 1H), 5.31 (s, 1H), 5.13 (m, 1H), 4.62-4.35 (m, 2H), 4.06 (s, 3H), 3.3 (m, 2H), 2.57 (s, 3H), 0.98 (s, 9H).

Provenance & Evidence