HCID 86700354, compound → HCID 86700356, compound

Participants

Reaction Steps

A solution of (S)-tert-butyl 3-(6-(6-(1-tert-butoxy-2-ethoxy-2-oxoethyl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-2-yl)-2-methyl-1H-benzo[d]imidazol-1-yl)azetidine-1-carboxylate (76 mg, 0.11 mmol) in 1.25 M HCl in i-PrOH (20 mL) was stirred at room temperature for 16 hours then at 45° C. for 3 hours. The solution was cooled to room temperature and concentrated in vacuo to provide the desired product. LCMS-ESI+: calc'd for C33H36ClN4O3S: 603.2 (M+H+); Found: 603.4 (M+H+).

Provenance & Evidence