HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86700362, compound → HCID 86700364, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86700362 | HCID 86700362 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 86700364 | HCID 86700364 | — |
Reaction Steps
A solution of (S)-tert-butyl 3-(6-(6-((S)-1-tert-butoxy-2-ethoxy-2-oxoethyl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-2-yl)-2-methyl-1H-benzo[d]imidazol-1-yl)pyrrolidine-1-carboxylate (70 mg, 0.10 mmol) in 1.25 M HCl in i-PrOH (20 mL) was stirred at 35° C. for 4 hours. The solution was then concentrated in vacuo to provide the desired product. LCMS-ESI+: calc'd for C34H38ClN4O3S: 617.2 (M+H+); Found: 617.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08987250B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-fad5241004a047c982731849f2d1f3e4 |
| Source note | uspto-grants-2015_03 |