(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(1,3-dimethyl-1H-indazol-6-yl)-5-methylbenzo[d]thiazol-6-yl)acetic acid → (S)-2-(2-(1-benzyl-3-methyl-1H-indazol-5-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetic acid

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Prepared in a manner similar to (S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(1,3-dimethyl-1H-indazol-6-yl)-5-methylbenzo[d]thiazol-6-yl)acetic acid, but using (S)-ethyl 2-(2-(1-benzyl-3-methyl-1H-indazol-5-yl)-7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyacetate instead of (S)-ethyl 2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(1,3-dimethyl-1H-indazol-6-yl)-5-methylbenzo[d]thiazol-6-yl)acetate. LCMS-ESI+: calc'd for C35H33ClN3O3S: 610.2 (M+H+); found: 610.3 (M+H+). 1H NMR (400 MHz, CD3OD) δ 8.47 (s, 1H), 8.12 (dd, J=7.6, 1.6 Hz, 1H), 7.89 (s, 1H), 7.78 (d, J=10 Hz, 1H), 7.69-7.62 (m, 4H), 7.40-7.27 (m, 4H), 5.66 (s, 2H), 5.34 (s, 1H), 2.69 (s, 3H), 2.68 (s, 3H), 0.98 (s, 9H).

Provenance & Evidence