{3-Methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl}boronic acid → (S)-ethyl 2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-yl)benzo[d]thiazol-6-yl)acetate

Participants

Reaction Steps

Prepared in a manner similar to (S)-ethyl 2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(1,3-dimethyl-1H-indazol-6-yl)-5-methylbenzo[d]thiazol-6-yl)acetate, but using 3-methyl-[1,2,4]triazolo[4,3-a]pyridin-7-ylboronic acid instead of 1,3-dimethyl-1H-indazol-6-ylboronic acid. 1H NMR (400 MHz, CDCl3) δ 8.25 (s, 1H), 7.94 (d, J=6.0 Hz, 1H), 7.91 (s, 1H), 7.75 (s, 1H), 7.58-7.49 (m, 3H), 7.49-7.44 (m, 1H), 5.17 (s, 1H), 4.26-4.16 (m, 2H), 2.81 (s, 3H), 2.61 (s, 3H), 1.26 (t, J=7.1 Hz, 3H), 0.98 (s, 9H).

Provenance & Evidence