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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 879592Generated: October 30, 2026

2-Methyl-2-(4-methylphenyl)morpholine → HCID 72194238, compound

https://huagongshe.com/reaction/879592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-2-(4-methylphenyl)morpholineHCID 24208807—
ReactantHCID 86700405HCID 86700405—
ProductHCID 72194238HCID 72194238—

Reaction Steps

(2S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methyl-2-(2-methyl-2-p-tolylmorpholino)benzo[d]thiazol-6-yl)acetic acid was prepared using the similar procedure as (2S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-2-(2-(4-chlorophenyl)-2-methylmorpholino)-5-methylbenzo[d]thiazol-6-yl)acetic acid except 2-(4-methylphenyl)-2-methylmorpholine was used instead of 2-(4-chlorophenyl)-2-methylmorpholine. LCMS-ESI+: calc'd for C32H35ClN2O4S: 579.2, 581.2 (M+H+); found: 579.4, 581.3 (M+H+). 1H-NMR: 400 MHz, (CD3OD) δ: 7.62 (m, 1H), 7.47-7.54 (m, 3H), 7.32 (m, 3H), 7.14 (m, 2H), 5.14 (s, 1H), 4.31 (t, J=12.8 Hz, 1H), 3.80 (m, 1H), 3.64 (m, 1H), 3.40-3.51 (m, 3H), 2.50 (s, 3H), 2.28 (s, 3H), 1.44 (s, 3H), 0.95 (s, 9H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08987250B2
Source datasetuspto-grants-2015_03
ORD IDord-22b55ca7cf0445129be74abb38c33579
Source noteuspto-grants-2015_03