Thionyl Chloride → HCID 86696919, compound

HRID 880049Notes

Reaction equation

HRID 880049 reaction equation
[C:1]1([N:7]2[C:12](=[O:13])[N:11]([CH2:14]CCC)[C:10](=[O:18])[C:9]([C:19]([OH:21])=O)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:24])=O>>[C:1]1([N:7]2[C:12](=[O:13])[N:11]([CH3:14])[C:10](=[O:18])[C:9]([C:19]([Cl:24])=[O:21])=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 86696921HCID 86696921, compound

Product 1

HCID 86696919HCID 86696919, compoundYield 88%

Procedure

Intermediate g (3.0 g, 0.01 mol) was added to thionyl chloride (10 V/W, 30 mL). The mixture was warmed up under stirring to react under reflux for 6 h. The solvent was evaporated off to produce a clear yellow crystal (3 g) in a yield of 88%,

Workup

  1. temperatureThe mixture was warmed up
  2. customto react
  3. temperatureunder reflux for 6 h
  4. customThe solvent was evaporated off

Sources & evidence

ORD record
ord-66cfc52be7f44c119ffa045b572da6f6
Source dataset
uspto-grants-2015_03
Patent number
US08993566B2

Reaction notes

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