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HRID880062

反应详情

EQUATION

反应方程式

HRID 880062 的结构方程式

REACTANTS

反应物

2
结构：Cl.Nc1ccsc1
HCID12413181

Thiophen-3-amine--hydrogen chloride (1/1)

C4H6ClNS

结构：O=C([O-])Cc1nc(N2CCOCC2)cc(=O)[nH]1.[Na+]
HCID136041844

未命名化合物

PRODUCTS

生成物

1
结构：O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1ccsc1
HCID136352178

未命名化合物

收率 82.2%

PROCEDURE

实验过程

The product is prepared according to the procedure described in Example 5, using 250 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 400 mg of 3-aminothiophene hydrochloride in place of the 2,4-difluoroaniline. 252 mg of 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]-N-(thiophen-3-yl)acetamide are obtained in the form of a beige solid, the characteristics of which are the following:

WORKUP

后处理

  1. customThe product is prepared