HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 136041737, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | m-Toluidine | HCID 7934 | — |
| Reactant | Sodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetate | HCID 136041844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 136041737 | HCID 136041737 | 59.7% |
Reaction Steps
The product is prepared according to the procedure described in Example 19, using 261 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate prepared in stage 2 of Example 1 and using a mixture of 1 ml of water and 9 ml of ethanol in place of the methanol and 214 mg of 3-methylaniline in place of the 3-(tert-butyl)aniline. 196 mg of N-(3-methylphenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993565B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-4b9c08cbf2764c41bb6c5978afefd678 |
| Source note | uspto-grants-2015_03 |