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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880097Generated: October 30, 2026

1,3-benzoxazol-4-amine → HCID 136041746, compound

https://huagongshe.com/reaction/880097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-benzoxazol-4-amineHCID 1482202—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136041746HCID 13604174654.6%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 260 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 268 mg of 1,3-benzoxazol-4-amine in place of the 2,4-difluoroaniline. 193 mg of N-(1,3-benzoxazol-4-yl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of an ecru solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993565B2
Source datasetuspto-grants-2015_03
ORD IDord-939d681b4fb34860a7698fea662e6706
Source noteuspto-grants-2015_03