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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880107Generated: October 30, 2026

2,3,4-Trifluoroaniline → HCID 136352197, compound

https://huagongshe.com/reaction/880107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3,4-TrifluoroanilineHCID 77468—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136352197HCID 13635219753.2%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 260 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 294 mg of 2,3,4-trifluoroaniline in place of the 2,4-difluoroaniline. 195 mg of 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]-N-(2,3,4-trifluorophenyl)acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993565B2
Source datasetuspto-grants-2015_03
ORD IDord-daf18fa8083c41e4ac0c2f679e9bbd43
Source noteuspto-grants-2015_03