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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880117Generated: November 1, 2026

4-Fluoro-3-nitroaniline → HCID 136041767, compound

https://huagongshe.com/reaction/880117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-3-nitroanilineHCID 67768—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136041767HCID 13604176746.9%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 500 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 510 mg of 4-fluoro-3-nitroaniline in place of the 2,4-difluoroaniline. 339 mg of N-(4-fluoro-3-nitrophenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993565B2
Source datasetuspto-grants-2015_03
ORD IDord-5cbc9748f3d24233864ccac06d2f850e
Source noteuspto-grants-2015_03