HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-fluoroaniline → HCID 136352204, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-fluoroaniline | HCID 242873 | — |
| Reactant | Sodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetate | HCID 136041844 | — |
| Product | HCID 136352204 | HCID 136352204 | 78.8% |
Reaction Steps
The product is prepared according to the procedure described in Example 5, using 250 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 260 mg of 2-bromo-4-fluoroaniline in place of the 2,4-difluoroaniline. 310 mg of N-(2-bromo-4-fluorophenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a brown solid, the characteristics of which are the following:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993565B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-26c10f99d6334975995a827c47aebc99 |
| Source note | uspto-grants-2015_03 |