Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880119Generated: October 31, 2026

2-Bromo-4-fluoroaniline → HCID 136352204, compound

https://huagongshe.com/reaction/880119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-4-fluoroanilineHCID 242873—
ReactantSodium (4-morpholin-4-yl-6-oxo-1,6-dihydropyrimidin-2-yl)acetateHCID 136041844—
ProductHCID 136352204HCID 13635220478.8%

Reaction Steps

The product is prepared according to the procedure described in Example 5, using 250 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate and 260 mg of 2-bromo-4-fluoroaniline in place of the 2,4-difluoroaniline. 310 mg of N-(2-bromo-4-fluorophenyl)-2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetamide are obtained in the form of a brown solid, the characteristics of which are the following:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993565B2
Source datasetuspto-grants-2015_03
ORD IDord-26c10f99d6334975995a827c47aebc99
Source noteuspto-grants-2015_03