Diethyl Ether → HCID 66759469, compound

Participants

Reaction Steps

To a stirred solution of 5-{2,4-bis[(2-methoxyethoxy)methoxy]-6-(4-nitrophenoxy)phenyl}isoxazole-3-carboxylic acid ethyl ester (15.6 g., 27.7 mmol) in ethanol (75 mL) was added a solution of 1 M KOH (55.5 mL, 55 mmol, 2 eq.) in ethanol at room temperature. After stirring overnight, the precipitate was collected and washed with a small volume of ethanol, then with ether to provide the title compound (12.3 g, 77% yield).

Provenance & Evidence