5-(Chloromethyl)-2-(trifluoromethyl)pyridine → [2-(Pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]-[4-[[6-(trifluoromethyl)pyridin-3-yl]methoxy]phenyl]methanone
Reaction equation
[Cl:21][CH2:22][c:23]1[cH:24][n:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH:11]([CH2:15][N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[N:10]2[CH:11]([CH2:15][N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1)[CH2:22][c:23]1[cH:24][n:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]1Participants
3
Sources & evidence
- ORD record
- ord-907367e24cec4b4db24a955bfdd2fc0b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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