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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880400Generated: October 31, 2026

2-Chloropyridine → HCID 9311031, compound

https://huagongshe.com/reaction/880400

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloropyridineHCID 7977—
Reactant1-(4-Nitrophenyl)piperazineHCID 80447—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 9311031HCID 9311031—

Reaction Steps

From 1-(4-nitro-phenyl)-piperazine and 2-chloropyridine, by heating in DMSO to give 1-(4-nitro-phenyl)-4-pyridin-2-yl-piperazine then catalytic hydrogenation over Raney nickel in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993574B2
Source datasetuspto-grants-2015_03
ORD IDord-5b920ecc428447aebbb0c5218ffaf717
Source noteuspto-grants-2015_03