1-(4-Nitrophenyl)piperazine → HCID 60874744, compound

HRID 880403Notes

Reaction equation

HRID 880403 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O.Cl[C:17]1[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][N:18]=1.CC1N=C(N2CCN(C3C=CC(N)=CC=3)CC2)C=CC=1>>[CH3:23][C:20]1[CH:21]=[CH:22][C:17]([N:13]2[CH2:14][CH2:15][N:10]([C:7]3[CH:8]=[CH:9][C:4]([NH2:1])=[CH:5][CH:6]=3)[CH2:11][CH2:12]2)=[N:18][CH:19]=1

Participants

4

Reactant 3

HCID 804471-(4-Nitrophenyl)piperazineHCID 5813932-Chloro-5-methyl-pyridineHCID 60875685HCID 60875685, compound

Product 1

HCID 60874744HCID 60874744, compound

Procedure

From 1-(4-nitro-phenyl)-piperazine and 2-chloro-5-methylpyridine, in the same manner as the preparation of 4-[4-(6-methyl-pyridin-2-yl)-piperazin-1-yl]-phenylamine.

Sources & evidence

ORD record
ord-48b318e05eba453290ec9ca9837277c3
Source dataset
uspto-grants-2015_03
Patent number
US08993574B2

Reaction notes

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