6-Ethylpyridin-2-amine → 4-[4-(6-Ethyl-pyridin-2-yl)-piperazin-1-yl]-phenylamine

HRID 880404Notes

Reaction equation

HRID 880404 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][CH3:9])[N:3]=1.C(C1C=CN=C(N2[CH2:23][CH2:22][N:21]([C:24]3[CH:29]=[CH:28][C:27]([NH2:30])=[CH:26][CH:25]=3)[CH2:20][CH2:19]2)C=1)C>>[CH2:8]([C:4]1[N:3]=[C:2]([N:1]2[CH2:19][CH2:20][N:21]([C:24]3[CH:25]=[CH:26][C:27]([NH2:30])=[CH:28][CH:29]=3)[CH2:22][CH2:23]2)[CH:7]=[CH:6][CH:5]=1)[CH3:9]

Participants

3

Reactant 2

HCID 890216-Ethylpyridin-2-amineHCID 668510314-[4-(4-Ethyl-pyridin-2-yl)-piperazin-1-yl]-phenylamine

Product 1

HCID 668512384-[4-(6-Ethyl-pyridin-2-yl)-piperazin-1-yl]-phenylamine

Procedure

From 2-amino-6-ethylpyridine, in the same manner as 4-[4-(4-ethyl-pyridin-2-yl)-piperazin-1-yl]-phenylamine.

Sources & evidence

ORD record
ord-fa6e63f839cf4bc8b0657a9e58aa9164
Source dataset
uspto-grants-2015_03
Patent number
US08993574B2

Reaction notes

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