Boron tribromide → HCID 66914765, compound

Participants

Reaction Steps

Boron tribromide (0.3 mL, 3.07 mmol) was added drop wise to a solution of 1-(2-methoxyethyl)-2-methyl-4-phenyl-pyrrole (330 mg, 1.53 mmol) in dry dichloromethane (20 mL) at 0 to 5° C. and stirred for 1 h. The reaction mixture was quenched with a 10% sodium bicarbonate solution (20 mL) at 0 to 5° C. and extracted with ethyl acetate (2×25 mL). The organic layer was washed successively with water (2×25 mL), brine (2×25 mL), dried over anhydrous sodium sulphate and concentrated in vacuo to yield 2-(2-methyl-4-phenyl-pyrrol-1-yl)-ethanol (270 mg, 88%) as a brown solid.

Provenance & Evidence