HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Fluoro-4-nitrobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Fluoro-4-nitrobenzoic acid | HCID 230653 | — |
| Product | 3-Fluoro-4-nitrobenzoyl chloride | HCID 2774656 | 99% |
Reaction Steps
A stirred solution of 3-fluoro-4-nitro-benzoic acid (1.65 g, 8.91 mmol) in thionyl chloride (10 mL) was heated at reflux for 2 h. Excess thionyl chloride was evaporated in vacuo and the residue azeotroped with toluene to afford 3-fluoro-4-nitro-benzoyl chloride (1.7 g, 99%) as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993574B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-8da9e7ed9518459a824ff103d4a188b8 |
| Source note | uspto-grants-2015_03 |