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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 880708Generated: October 27, 2026

Trifluoroacetic acid → HCID 67423431, compound

https://huagongshe.com/reaction/880708

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67423451HCID 67423451—
SolventDichloromethaneHCID 6344—
ProductHCID 67423431HCID 6742343190%

Reaction Steps

In a 25 ml round-bottomed flask, 1 g of 3-(2,4-bis(benzyloxy)phenyl)azetidine-1-carboxylic acid tert-butyl ester is dissolved in 10 ml of dichloromethane and then 2.5 ml of trifluoroacetic acid are added. The reaction mixture is stirred for 2 hours. The solvents are evaporated off and the residue is then taken up in isopropyl ether. 0.92 g of 3-(2,4-bis(benzyloxy)phenyl)azetidine trifluoroacetate is obtained. Yield=90%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993596B2
Source datasetuspto-grants-2015_03
ORD IDord-c10e6be9467545d4870f8d7de3fb390f
Source noteuspto-grants-2015_03