HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(6-acetyl-2-chloro-3-methoxyphenyl)-2-(trifluoromethyl)thiazole-4-carboxamide → HCID 178487684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(6-acetyl-2-chloro-3-methoxyphenyl)-2-(trifluoromethyl)thiazole-4-carboxamide | HCID 68792612 | — |
| Reactant | HCID 178437375 | HCID 178437375 | — |
| Product | HCID 178487684 | HCID 178487684 | 26% |
Reaction Steps
Compound 255a (white solid) was synthesized from compound 254a (1 g, 1 eq.) in 26% yield, following the procedure as described for compound 209a. 1H NMR (CDCl3, 400 MHz): δ (ppm) 4.07 (s, 3H), 6.78 (s, 1H), 7.09 (d, J=9.13 Hz, 1H), 8.14 (s, 1H), 8.30 (d, J=9.13 Hz, 1H), 9.93 (s, 1H); 19F NMR (CDCl3, 376 MHz): δ (ppm) −61.14 (s, 3F); MS (ESI, EI+): m/z=360.91 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993595B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-8234d51550c04b4aa1de82d6f9ea3861 |
| Source note | uspto-grants-2015_03 |