HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Bromo-3-methoxyisoquinoline → 3-Methoxyisoquinoline-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Bromo-3-methoxyisoquinoline | HCID 67491766 | — |
| Reactant | 7-(trifluoromethyl)-1H-indazole-5-carboxylic acid | HCID 67491810 | — |
| Product | 3-Methoxyisoquinoline-7-carboxylic acid | HCID 67491428 | — |
Reaction Steps
The title compound was prepared by a method analogous to that described in Steps 3-4 of Intermediate 21, using 7-bromo-3-methoxyisoquinoline. +ESI (M+H) 204.2; 1H NMR (400 MHz, CD3OD, δ): 9.08 (s, 1H), 8.71 (s, 1H), 8.14 (dd, J=8.78, 1.56 Hz, 1H), 7.83 (d, J=8.78 Hz, 1H), 7.17 (s, 1H), 4.02 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993586B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-9a6a88c60ae6462994cfaa949b06a6bb |
| Source note | uspto-grants-2015_03 |