2-(2,5-Dichloropyrimidin-4-ylamino)-3-fluoro-N-methyl-benzamide → 2-{5-Chloro-2-[5,5-dimethyl-2-oxo-3-(2,2,2-trifluoro-acetylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-8-ylamino]-pyrimidin-4-ylamino}-3-fluoro-N-methyl-benzamide
Reaction equation
[Cl:23][c:24]1[n:25][cH:26][c:27]([Cl:42])[c:28]([NH:30][c:31]2[c:32]([C:33](=[O:34])[NH:35][CH3:36])[cH:37][cH:38][cH:39][c:40]2[F:41])[n:29]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:21][cH:22]1)[C:6]([CH3:19])([CH3:20])[CH2:7][CH:8]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[C:9](=[O:11])[NH:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:21][cH:22]1)[C:6]([CH3:19])([CH3:20])[CH2:7][CH:8]([NH:12][C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[C:9](=[O:11])[NH:10]2)[c:24]1[n:25][cH:26][c:27]([Cl:42])[c:28]([NH:30][c:31]2[c:32]([C:33](=[O:34])[NH:35][CH3:36])[cH:37][cH:38][cH:39][c:40]2[F:41])[n:29]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-4ea0d08c158c4543a4a2f6bc98e270ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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